USE

SYNTHROID® (levothyroxine sodium tablets, USP) is a prescription, man-made thyroid hormone that is used to treat a condition called hypothyroidism, except in cases of temporary hypothyroidism, which is usually associated with an inflammation of the thyroid gland (thyroiditis). It is meant to replace a hormone that is usually made by your thyroid gland. Generally, thyroid replacement treatment is to be taken for life.

SAFETY CONSIDERATIONS

Thyroid hormones, including SYNTHROID, should not be used either alone or in combination with other drugs for the treatment of obesity or weight loss. In patients with normal thyroid levels, doses of SYNTHROID used daily for hormone replacement are not helpful for weight loss. Larger doses may result in serious or even life-threatening events, especially when used in combination with certain other drugs used to reduce appetite.

WHAT ARE SOME
OF THE RISK
FACTORS FOR
HYPOTHYROIDISM?

Hypothyroidism is one of the most common thyroid diseases. It affects people all over the world of every age, sex, race, and level of wealth and education. But some people have a greater risk of developing it. Here are some risk factors for developing hypothyroidism:

  • Being a woman
  • Having a close relative with thyroid disease
  • Having an autoimmune disease such as type 1 diabetes or rheumatoid arthritis

The only way to know for sure if you have hypothyroidism is to see your doctor for a proper diagnosis.

WHAT ARE SOME OF THE COMMON CAUSES OF HYPOTHYROIDISM?

HASHIMOTO’S DISEASE

This condition is an autoimmune disease that causes the thyroid to become inflamed, which affects the thyroid’s ability to produce hormones and often results in hypothyroidism.

SURGICAL REMOVAL OF THE THYROID GLAND

In cases such as thyroid cancer, the thyroid gland may need to be partially or entirely removed. This can be a cause of hypothyroidism.

RADIATION THERAPY FOR HEAD AND NECK DISEASE

Radiation treatment can cause total or partial loss of thyroid function, resulting in hypothyroidism.

HYPERTHYROIDISM TREATMENT

Sometimes people with hyperthyroidism (thyroid gland makes too much of the hormone thyroxine) are treated with radioactive iodine or anti-thyroid medications. These treatments sometimes cause hypothyroidism.

Certain medications

Medications like lithium (used to treat certain psychiatric disorders) and sulfonamides used to treat diabetes can cause the thyroid to make less thyroid hormone, resulting in hypothyroidism.

Less common causes of hypothyroidism include congenital disease (defective thyroid gland or no thyroid gland at birth), disorder of the pituitary gland (pea-sized gland located in the brain), iodine deficiency, and other conditions.

Use

SYNTHROID® (levothyroxine sodium tablets, USP) is a prescription, man-made thyroid hormone that is used to treat a condition called hypothyroidism, except in cases of temporary hypothyroidism, which is usually associated with an inflammation of the thyroid gland (thyroiditis). It is meant to replace a hormone that is usually made by your thyroid gland. Generally, thyroid replacement treatment is to be taken for life.

Important Safety Information

  • Thyroid hormones, including SYNTHROID, should not be used either alone or in combination with other drugs for the treatment of obesity or weight loss. In patients with normal thyroid levels, doses of SYNTHROID used daily for hormone replacement are not helpful for weight loss. Larger doses may result in serious or even life-threatening events, especially when used in combination with certain other drugs used to reduce appetite.

  • Do not use SYNTHROID if you have hyperthyroidism or over-active thyroid, uncorrected adrenal problems, are having symptoms of a heart attack, or are allergic to any of its ingredients.

  • In women, long-term treatment with SYNTHROID has been associated with increased bone loss, especially in women who are on high doses or those who are on high doses after menopause.

  • Tell your doctor if you are allergic to any foods or drugs, are pregnant or plan to become pregnant, are breast-feeding or are taking any other drugs, as well as prescription and over-the-counter products.

  • Tell your doctor about any other medical conditions you may have, especially heart disease, diabetes, blood clotting problems, and adrenal or pituitary gland problems. The dose of other drugs you may be taking to control these conditions may have to be changed while you are taking SYNTHROID. If you have diabetes, check your blood sugar levels and/or the glucose in your urine, as ordered by your doctor and immediately tell your doctor if there are any changes. If you are taking blood thinners, your blood clotting status should be checked often.

  • Use SYNTHROID only as ordered by your doctor. Do not stop or change the amount you take, or how often you take it, unless told to do so by your doctor.

  • Products such as iron and calcium supplements and antacids can lower your body’s ability to absorb SYNTHROID, so SYNTHROID should be taken 4 hours before or after taking these products.

  • Take SYNTHROID as a single dose, preferably on an empty stomach, one-half to one hour before breakfast. Your body’s ability to absorb SYNTHROID is improved when you take it on an empty stomach.

  • Tell your doctor if you develop any of the following symptoms: rapid or abnormal heartbeat, chest pain, difficulty catching breath, leg cramps, headache, feeling nervous, irritability, sleeplessness, shaking, change in appetite, weight gain or loss, throwing up, diarrhea, increased sweating, unable to tolerate heat, fever, changes in menstrual periods, swollen red bumps on the skin or skin rash, or any other unusual medical event.

  • Tell your doctor or dentist that you are taking SYNTHROID before any surgery.

  • Once your body’s response to SYNTHROID has stabilized, it is important to have lab tests done, as ordered by your doctor, at least once a year.

This is the most important safety information you should know about SYNTHROID. For more information, talk with your doctor.

SYNTHROID TABLETS ARE A PRESCRIPTION MEDICATION.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

If you cannot afford your medication, contact www.pparx.org for assistance.

Coming soon!
Our very own YouTube Channel, where you can watch other people's stories with hypothyroidism.

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Use

SYNTHROID® (levothyroxine sodium tablets, USP) is a prescription, man-made thyroid hormone that is used to treat a condition called hypothyroidism, except in cases of temporary hypothyroidism, which is usually associated with an inflammation of the thyroid gland (thyroiditis). It is meant to replace a hormone that is usually made by your thyroid gland. Generally, thyroid replacement treatment is to be taken for life.

Important Safety Information

  • Thyroid hormones, including SYNTHROID, should not be used either alone or in combination with other drugs for the treatment of obesity or weight loss. In patients with normal thyroid levels, doses of SYNTHROID used daily for hormone replacement are not helpful for weight loss. Larger doses may result in serious or even life-threatening events, especially when used in combination with certain other drugs used to reduce appetite.

  • Do not use SYNTHROID if you have hyperthyroidism or over-active thyroid, uncorrected adrenal problems, are having symptoms of a heart attack, or are allergic to any of its ingredients.

  • In women, long-term treatment with SYNTHROID has been associated with increased bone loss, especially in women who are on high doses or those who are on high doses after menopause.

  • Tell your doctor if you are allergic to any foods or drugs, are pregnant or plan to become pregnant, are breast-feeding or are taking any other drugs, as well as prescription and over-the-counter products.

  • Tell your doctor about any other medical conditions you may have, especially heart disease, diabetes, blood clotting problems, and adrenal or pituitary gland problems. The dose of other drugs you may be taking to control these conditions may have to be changed while you are taking SYNTHROID. If you have diabetes, check your blood sugar levels and/or the glucose in your urine, as ordered by your doctor and immediately tell your doctor if there are any changes. If you are taking blood thinners, your blood clotting status should be checked often.

  • Use SYNTHROID only as ordered by your doctor. Do not stop or change the amount you take, or how often you take it, unless told to do so by your doctor.

  • Products such as iron and calcium supplements and antacids can lower your body’s ability to absorb SYNTHROID, so SYNTHROID should be taken 4 hours before or after taking these products.

  • Take SYNTHROID as a single dose, preferably on an empty stomach, one-half to one hour before breakfast. Your body’s ability to absorb SYNTHROID is improved when you take it on an empty stomach.

  • Tell your doctor if you develop any of the following symptoms: rapid or abnormal heartbeat, chest pain, difficulty catching breath, leg cramps, headache, feeling nervous, irritability, sleeplessness, shaking, change in appetite, weight gain or loss, throwing up, diarrhea, increased sweating, unable to tolerate heat, fever, changes in menstrual periods, swollen red bumps on the skin or skin rash, or any other unusual medical event.

  • Tell your doctor or dentist that you are taking SYNTHROID before any surgery.

  • Once your body’s response to SYNTHROID has stabilized, it is important to have lab tests done, as ordered by your doctor, at least once a year.

This is the most important safety information you should know about SYNTHROID. For more information, talk with your doctor.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you cannot afford your medication, contact www.pparx.org for assistance.