USE: SYNTHROID® (levothyroxine sodium) tablets, USP

for oral use is a prescription, man-made thyroid hormone that is used to treat a condition called hypothyroidism. It is meant to replace a hormone that is usually made by your thyroid gland. Generally, thyroid replacement treatment is to be taken for life. SYNTHROID should not be used to treat noncancerous growths or enlargement of the thyroid in patients with normal iodine levels, or in cases of temporary hypothyroidism caused by inflammation of the thyroid gland (thyroiditis).

IMPORTANT SAFETY INFORMATION

  • Thyroid hormones, including SYNTHROID, should not be used either alone or in combination with other drugs for the treatment of obesity or weight loss. In patients with normal thyroid levels, doses of SYNTHROID used daily for hormone replacement are not helpful for weight loss. Larger doses may result in serious or even life-threatening events, especially when used in combination with certain other drugs used to reduce appetite.

  • Do not use SYNTHROID if you have uncorrected adrenal problems.

  • Taking too much levothyroxine has been associated with increased bone loss, especially in women after menopause.

  • Once your doctor has found your specific SYNTHROID dose, it is important to have lab tests done, as ordered by your doctor, at least once a year.

  • Foods like soybean flour, cottonseed meal, walnuts, and dietary fiber may cause your body to absorb less SYNTHROID from the gastrointestinal tract. Grapefruit juice may cause your body to absorb less levothyroxine and may reduce its effect. Let your doctor know if you eat these foods, as your dose of SYNTHROID may need to be adjusted.

  • Use SYNTHROID only as ordered by your doctor. Take SYNTHROID as a single dose, preferably on an empty stomach, one-half to one hour before breakfast.

  • Products such as iron and calcium supplements and antacids can lower your body’s ability to absorb levothyroxine, so SYNTHROID should be taken 4 hours before or after taking these products.

  • Tell your doctor if you are pregnant or breastfeeding or are thinking of becoming pregnant while taking SYNTHROID. Your dose of SYNTHROID may need to be increased during your pregnancy.

  • It may take several weeks before you notice an improvement in your symptoms.

  • Tell your doctor if you are taking any other drugs, including prescription and over-the-counter products.

  • Tell your doctor about any other medical conditions you may have, especially heart disease, diabetes, blood clotting problems, and adrenal or pituitary gland problems. The dose of other drugs you may be taking to control these conditions may have to be changed while you are taking SYNTHROID. If you have diabetes, check your blood sugar levels and/or the glucose in your urine, as ordered by your doctor, and immediately tell your doctor if there are any changes. If you are taking blood thinners, your blood clotting status should be checked often.

  • Tell your doctor or dentist that you are taking SYNTHROID before any surgery.

  • Tell your doctor if you develop any of the following symptoms: rapid or abnormal heartbeat, chest pain, difficulty catching your breath, leg cramps, headache, nervousness, irritability, sleeplessness, shaking, change in appetite, weight gain or loss, vomiting, diarrhea, increased sweating, difficulty tolerating heat, fever, changes in menstrual periods, swollen red bumps on the skin (hives) or skin rash, or any other unusual medical event.

  • Partial hair loss may occur during the first few months you are taking SYNTHROID.

This is the most important safety information you should know about SYNTHROID. For more information, talk with your doctor.

Click here for full Prescribing Information or go to http://www.rxabbvie.com/pdf/synthroid.pdf.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

If you cannot afford your medication, contact www.pparx.org for assistance.

Living with
hypothyroidism

Hear from people living with hypothyroidism

There are millions of us living with hypothyroidism. We’ve all got questions. But we’ve also got a community we can count on for answers. From healthcare professionals to people like you living with hypothyroidism, you can learn more about what it really means to better live your life while managing your hypothyroidism.

Video Gallery

Different perspectives on hot topics in the hypothyroidism community

DR LEVY ON UNDERSTANDING
YOUR TREATMENT

Dr Levy covers what to expect from Synthroid at the start of treatment and throughout your course of therapy, plus ways to help you manage your hypothyroidism.

DR SEIBEL ON TAKING SYNTHROID AND TAKING AN ACTIVE ROLE

Dr Seibel explains the right way to take Synthroid and importance of taking an active role in your treatment—from the pharmacy to the doctor-patient relationship.

DR ROSENTHAL ON
HOW TO TAKE SYNTHROID

Dr Rosenthal discusses the importance of taking Synthroid every morning, tips for making it part of your morning routine, and ensuring you get what your doctor prescribed.

DR SEIBEL SUGGESTS THAT PATIENTS DOUBLE-CHECK THEIR PILLS

Learn tips on making sure the pharmacist gives you Synthroid every time you fill a prescription.

DR ROSENTHAL ON
HOW TO MAKE SURE
IT'S SYNTHROID

Dr Rosenthal shares his steps for helping ensure his patients get the medication he prescribed.

People living with
hypothyroidism

ELISA AND TRACY ON WHAT PREGNANT WOMEN NEED TO KNOW ABOUT HYPOTHYROIDISM

Learn about how to work with your doctor to help manage your hypothyroidism during pregnancy.

ELISA AND TRACY ON WHAT WELL‐MANAGED HYPOTHYROIDISM LOOKS LIKE

Learn what TSH means and how your TSH number will help you and your doctor effectively manage your hypothyroidism.

ELISA AND TRACY ON CREATING A MORNING ROUTINE FOR TAKING SYNTHROID

Start your day by consistently taking Synthroid before eating, and know what foods and supplements can interfere with the way your body absorbs Synthroid.

ELISA AND TRACY ON WHY YOU SHOULD MAKE SURE YOU’RE GETTING SYNTHROID

Learn how to check your pills and talk to the pharmacist to make sure you get exactly what your doctor prescribed.

ELISA LEARNS THAT KNOWLEDGE IS POWER WITH HYPOTHYROIDISM

Elisa shares her story on finding the right support, the right community, and getting a grasp on her health.

LIBBY GAINS CLARITY THROUGH UNDERSTANDING

It wasn't until Libby found out she was pregnant that she knew she had to take charge of her hypothyroidism.

MALIA ON HER LONG OVERDUE ASSESSMENT

Learn about Malia's hypothyroidism empowerment journey—finding answers and being prescribed Synthroid.

PAM ON TAKING THE INITIATIVE

Find out how Pam reached her "ah-ha" moment in her hypothyroidism diagnosis.

WENDY AND LAURA'S STORIES: A TWIN-SISTER STORY

Identical twins Wendy and Laura share their hypothyroidism stories and how they have proactively dealt with the disease.

NABEEHA SHARES HOW SHE TAKES A PROACTIVE ROLE IN HER HEALTH

Nabeeha, a busy working mother of 2, talks about the importance of over-communicating with her doctor and loved ones about how she’s feeling.

Story Gallery

Learn how Kelley uses a weekly pillbox for her Synthroid morning routine

Kelley on her Synthroid morning routine

Synthroid is part of my morning routine. Presently, I don’t even think about it. It happens naturally. I wake up, reach to my bedside table, and take my Synthroid. I have never...
missed a dose. I keep my Synthroid in a pillbox marked with the days of the week. This way I can take a look to ensure that I took my Synthroid each morning and did not miss a dose. I keep a glass of water by the pillbox so everything is there just when I need it.
–Kelley

Read More

Click to expand
Learn how Wendy sticks to her Synthroid morning routine by keeping Synthroid next to a water glass

WENDY ON HER
morning routine

Every day starts with me immediately going into the kitchen to take my medication and drink water. I then go to the bathroom and then head to the kids’ rooms or elsewhere in the house to do whatever I do next. I am committed to not eating for at least 30 minutes...
, and my entire family is fully aware of my morning medication routine. My medication is kept in the top drawer of my bathroom cabinet, and I keep a glass or water bottle on the counter next to the sink. Both are easy to get to for me. I quickly learned how to take my medication—in the morning with a glass of water at least 30 minutes prior to eating anything. I have made this my routine every day.
–Wendy

Read More

Click to expand
Learn how Laura’s family members are involved in her Synthroid morning routine

Laura’s morning
routine

My morning routine starts with Synthroid. Just after turning off my alarm clock, I grab my Synthroid in the same motion. With a water bottle or glass of water usually right there on my nightstand, I take my Synthroid and drink my water...
sitting in bed before my feet even hit the floor. The next 40-plus minutes go by fast as I shower, get dressed, and get ready for the day. By the time I am done getting myself ready, it has been 40-plus minutes and I am ready to eat a quick breakfast and/or grab a mug of coffee. My family is used to this routine. My husband knows the drill. I shower and get ready in the bathroom first, and eat breakfast second. It’s important to have a family member who understands the importance of how and when to take Synthroid and is willing to help create and support the routine, too.
–Laura

Read More

Click to expand
Learn how Malia makes Synthroid part of her morning routine as a stay-at-home mom

MALIa’s morning
routine

I get up and I reach for the Synthroid and my water. I am sadly one of those people who, first thing after waking, will check my email and texts from the night before (I turn the ringer off at night). That kind of kills time and...
That kind of kills time and has become sort of a ritual/timer for me. It also lets me know what things are urgent to deal with before I get distracted with other things. Then I get up and brush teeth, wash face, etc. Because I am a stay-at-home mom and a homeschooler, I know once I put on the “mom” hat with the kids, everything is on “go.” I have never been the type to stay in pajamas all day, so by the time I do everything to get my day started and actually fix breakfast, it’s easily an hour later.
–Malia

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Click to expand
Learn how Pam’s granddaughter is part of her Synthroid morning routine

PAM’s morning
routine

It’s 7:30 am and I’m getting up, and on the shelf are my medications. I get my Synthroid out. After all these years, it is easy for me to spot my Synthroid. I take my Synthroid with an 8-ounce glass of water. Then I start the coffee pot...
for my next bit of joy in the morning—the smell of fresh brewed coffee and the thought of that first cup of coffee in a half hour or a little longer. I then let the dogs outside, and they are fed and hydrated. Usually a load of laundry is started. I soon hear the patter of little feet. I am blessed by a little angel that comes downstairs from her room after a night’s sleep. She says, “Nana, love you, hugs,” and we hug and kiss good morning. Then we continue with potty training. My granddaughter likes to watch a few morning cartoons, and I turn on the TV for her and go and let the dogs back in. By then the coffee’s ready and it is a half hour or more later, and I have that first cup of coffee.
–Pam

Read More

Click to expand
Click to find out how Wendy learns and asks questions about hypothyroidism

Wendy on learning and
asking questions

Since being diagnosed at such a young (and clueless) age, I know to look at every condition, whether temporary or permanent, as another opportunity...
for me to learn something new. I take it upon myself to do research about my condition and to be very open in discussing it with my doctor as well. Knowledge is incredible power. I never stop learning. I never stop asking questions. I never stop taking charge!
–Wendy

Read More

Click to expand
Click to read more on Wendy checking her pill

Wendy on checking
her pill

At the age of 38, I have been seeing the same doctor for a few years now, and his office has it clearly marked in my records that my doctor prefers Synthroid. I check...
that each prescription/renewal says “Synthroid” as my doctor prefers. They are very good about specifying “Synthroid” clearly on each prescription written. I also have a great relationship with my local pharmacy, and they also have it clearly marked in my records. I make sure to check my pill bottle and the actual pills before leaving the pharmacy, just to make sure. I know to look for a pink pill that’s 200 mcg dosage and that’s stamped with the dosage and the “SYNTHROID” name on the pill. I also check the manufacturer on the bottle to make sure it says AbbVie.
–Wendy
The Food and Drug Administration has determined that certain levothyroxine products are interchangeable. The FDA has determined that drugs that are classified as interchangeable can be substituted at the pharmacy. A levothyroxine product that is not interchangeable with Synthroid might not have the exact same effect on your TSH as Synthroid.

Read More

Click to expand
Click to read more about how Laura ensures she gets Synthroid

Laura on making sure she gets Synthroid

To make sure I’m getting the Synthroid my doctor prescribed, I always open the bottle and look at the pills when I pick it up. I know what color pill I take currently, and I look...
for the actual name “SYNTHROID” on my pill.
–Laura
The Food and Drug Administration has determined that certain levothyroxine products are interchangeable. The FDA has determined that drugs that are classified as interchangeable can be substituted at the pharmacy. A levothyroxine product that is not interchangeable with Synthroid might not have the exact same effect on your TSH as Synthroid.

Read More

Click to expand

USE

SYNTHROID® (levothyroxine sodium) tablets, for oral use is a prescription, man-made thyroid hormone that is used to treat a condition called hypothyroidism. It is meant to replace a hormone that is usually made by your thyroid gland. Generally, thyroid replacement treatment is to be taken for life. SYNTHROID should not be used to treat noncancerous growths or enlargement of the thyroid in patients with normal iodine levels, or in cases of temporary hypothyroidism caused by inflammation of the thyroid gland (thyroiditis).

IMPORTANT SAFETY INFORMATION

  • Thyroid hormones, including SYNTHROID, should not be used either alone or in combination with other drugs for the treatment of obesity or weight loss. In patients with normal thyroid levels, doses of SYNTHROID used daily for hormone replacement are not helpful for weight loss. Larger doses may result in serious or even life-threatening events, especially when used in combination with certain other drugs used to reduce appetite.

  • Do not use SYNTHROID if you have uncorrected adrenal problems.

  • Taking too much levothyroxine has been associated with increased bone loss, especially in women after menopause.

  • Once your doctor has found your specific SYNTHROID dose, it is important to have lab tests done, as ordered by your doctor, at least once a year.

  • Foods like soybean flour, cottonseed meal, walnuts, and dietary fiber may cause your body to absorb less SYNTHROID from the gastrointestinal tract. Grapefruit juice may cause your body to absorb less levothyroxine and may reduce its effect. Let your doctor know if you eat these foods, as your dose of SYNTHROID may need to be adjusted.

  • Use SYNTHROID only as ordered by your doctor. Take SYNTHROID as a single dose, preferably on an empty stomach, one-half to one hour before breakfast.

  • Products such as iron and calcium supplements and antacids can lower your body’s ability to absorb levothyroxine, so SYNTHROID should be taken 4 hours before or after taking these products.

  • Tell your doctor if you are pregnant or breastfeeding or are thinking of becoming pregnant while taking SYNTHROID. Your dose of SYNTHROID may need to be increased during your pregnancy.

  • It may take several weeks before you notice an improvement in your symptoms.

  • Tell your doctor if you are taking any other drugs, including prescription and over-the-counter products.

  • Tell your doctor about any other medical conditions you may have, especially heart disease, diabetes, blood clotting problems, and adrenal or pituitary gland problems. The dose of other drugs you may be taking to control these conditions may have to be changed while you are taking SYNTHROID. If you have diabetes, check your blood sugar levels and/or the glucose in your urine, as ordered by your doctor, and immediately tell your doctor if there are any changes. If you are taking blood thinners, your blood clotting status should be checked often.

  • Tell your doctor or dentist that you are taking SYNTHROID before any surgery.

  • Tell your doctor if you develop any of the following symptoms: rapid or abnormal heartbeat, chest pain, difficulty catching your breath, leg cramps, headache, nervousness, irritability, sleeplessness, shaking, change in appetite, weight gain or loss, vomiting, diarrhea, increased sweating, difficulty tolerating heat, fever, changes in menstrual periods, swollen red bumps on the skin (hives) or skin rash, or any other unusual medical event.

  • Partial hair loss may occur during the first few months you are taking SYNTHROID.

This is the most important safety information you should know about SYNTHROID. For more information, talk with your doctor.

Click here for full Prescribing Information or go to http://www.rxabbvie.com/pdf/synthroid.pdf.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

If you cannot afford your medication, contact www.pparx.org for assistance.

SYNTHROID TABLETS ARE A PRESCRIPTION MEDICATION.