Taking Synthroid Tips to help you stay on track with your treatment

How you take Synthroid matters. Explore the tabs below to find everything from factors your doctor will consider when choosing your starting dose, to what you can expect long term. As always, be sure to follow up with your doctor on any questions you may have at your next appointment.

Precise dosing matters

There's no one dose that's right for all people with hypothyroidism. That's why Synthroid comes in a variety of dosing strengths to match each person's exact needs.

Dosing options to fit your needs

Synthroid comes in 12 dosing options to help your doctor find the dose that's right for you. Your doctor will determine your starting dose based on your weight, age, cause of hypothyroidism, and other health conditions, as well as other medications you’re taking.

Tablets shown not actual size and may not represent exact color.

Real Synthroid stories

Finding the right dose

Hear the steps Wendy took to make sure she found the right doctor—and the right dose.

What to expect when starting Synthroid

When you first start taking Synthroid, your doctor will usually test your TSH levels every 6 to 8 weeks. Because your thyroid hormone needs are very precise, your doctor may need to make small adjustments to find the dose that’s right for you.

It may take several weeks before you notice Synthroid is working and for your thyroid hormone levels to adjust to the correct range. 

How to take Synthroid the right way, every day

The way you take Synthroid can affect how much medicine your body is getting. That's why it's critical to take Synthroid as your doctor prescribes, and to take it the same way, every day.

Remember these quick tips on how to take Synthroid:

Once a day

Take Synthroid once a day, every day, at the same time before breakfast.

On an empty stomach

Only take Synthroid with water and on an empty stomach.

Wait 30 minutes

Wait 30 minutes to 1 hour before eating or drinking anything other than water.

Stay on track with your treatment

Keep this cheat sheet handy for fast facts about Synthroid and how to take it the right way.

Download cheat sheet

Myths vs Facts

It may take time to find the proper dose of Synthroid that restores your thyroid hormone levels. What do you think, is this a myth or a fact?

Sorry, that's incorrect. This is a fact.

It may take time to find the proper dose of Synthroid that restores your thyroid hormone levels.

It may take up to several weeks for you and your doctor to find the dose of Synthroid that works best for you. Then, after finding the right dose, it’s up to you to take your Synthroid the right way, every day, so that it can work properly. You can review how to take Synthroid here.

See more myths vs facts

Correct! This is a fact.

It may take time to find the proper dose of Synthroid that restores your thyroid hormone levels.

It may take up to several weeks for you and your doctor to find the dose of Synthroid that works best for you. Then, after finding the right dose, it’s up to you to take your Synthroid the right way, every day, so that it can work properly. You can review how to take Synthroid here.

See more myths vs facts

Perfecting your Synthroid routine

Establish your dosing routine to help you remember to take Synthroid the same way, every day.

Here are a few helpful suggestions:

  • Keep Synthroid in sight

    Keep Synthroid beside something you see or use when you wake up in the morning. It could be by your phone, toothbrush, or keys.

  • Stick a note where you’ll see it

    If you walk your dog every morning, place a sticky note near the leash. If you read the morning news on your smartphone or tablet, place a sticky note on it.

  • Map out your medication schedule

    Use a weekly pillbox to help you plan timing for your medication and avoid dosing errors.

  • Remember when you’ve taken Synthroid

    Turn your medicine bottle or weekly pillbox upside down after you take Synthroid. Before going to sleep, turn your bottle right side up so you know to take Synthroid in the morning.

  • Never miss a dose

    You can also sign up to get daily reminders via text or email to take your Synthroid.

    Looking to take advantage of these helpful reminder tools?

Remember: Avoid these foods and supplements

Foods that interfere with Synthroid

Foods containing soy and cottonseed meal can make Synthroid less effective. Walnuts, grapefruit juice, and dietary fiber can also make Synthroid less effective. If you eat any of these on a regular basis, check with your doctor. They may need to adjust your dose of Synthroid.

Supplements that interfere with Synthroid

Some supplements and medications can also interfere with the way Synthroid works. To avoid this, you should take Synthroid 4 hours before or after taking:

  • Iron supplements or multivitamins with iron
  • Calcium supplements or multivitamins with calcium
  • Antacids
  • Biotin/vitamin B7 (discontinue use at least 48 hours before any thyroid-function tests your doctor may want to administer)

Commonly asked questions

Are you sure you're taking Synthroid?

Many people who think they're taking Synthroid might actually be taking a generic.

How to make sure it’s Synthroid

Did you know: 1 out of every 3 people who think they’re taking Synthroid aren’t

Although your doctor may have prescribed Synthroid in some cases it can be switched to a generic brand at the pharmacy without you even realizing it.

That’s because some generics come in the same shapes, colors, and doses as Synthroid.

The Food and Drug Administration has determined that certain levothyroxine products are interchangeable and can be substituted at the pharmacy.

Make sure you’re getting what your doctor prescribed

You worked closely with your doctor to find the dose of Synthroid that’s right for you, so if your doctor prefers for you to stay on Synthroid, here are ways to make sure you get brand name Synthroid.

Enroll in the Synthroid Delivers Program

To make it even simpler to make sure you always get Synthroid, enroll in the Synthroid Delivers Program and have Synthroid delivered right to your door for only $25 a month for a 90-day prescription.*

*Other pricing available for 30 days ($29.50) and 60 days ($54). See full pricing information. Terms, conditions, and eligibility restrictions apply.

Ask your doctor to note their preference on your prescription

Without specific instructions for the pharmacy, such as DAW or “Dispense As Written,” you may get switched to another treatment without your knowledge, depending on your state’s pharmacy laws.

Inform your pharmacist

Always let your pharmacist or mail-order pharmacy know that you and your doctor prefer brand-name Synthroid.

Check your pills

Before leaving the pharmacy (or as soon as your prescription arrives in the mail), check the pill to ensure it says “SYNTHROID.” If it doesn’t, let your pharmacist know what you and your doctor prefer.

Real Synthroid stories

Making sure it’s Synthroid

Find out how Wendy works with her doctor and her pharmacy to make sure she’s getting brand-name Synthroid, as her doctor prescribed.

Myths vs Facts

When your doctor prescribes Synthroid, that might not always be what you'll get at the pharmacy. What do you think, is this a myth or a fact?

Sorry, that's incorrect. This is a fact.

1 in 3 people who think they are taking Synthroid aren’t. The FDA has determined that certain levothyroxine products are interchangeable and can be switched at the pharmacy. So if your doctor didn’t note their preference for brand-name Synthroid on the prescription, your pharmacy may switch you to a generic. To ensure you get what your doctor prescribed, check out these tips.

See more myths vs facts

Correct! This is a fact.

1 in 3 people who think they are taking Synthroid aren’t. The FDA has determined that certain levothyroxine products are interchangeable and can be switched at the pharmacy. So if your doctor didn’t note their preference for brand-name Synthroid on the prescription, your pharmacy may switch you to a generic. To ensure you get what your doctor prescribed, check out these tips.

See more myths vs facts

Stay on track with your treatment

Keep this cheat sheet handy for fast facts about Synthroid and how to take it the right way.

Download cheat sheet

What to expect as you continue taking Synthroid

Hypothyroidism is a lifelong condition that requires lifelong treatment. By continuing to take Synthroid as your doctor prescribed and getting your levels checked regularly, you can help keep your thyroid hormone levels where they should be.

Real Synthroid stories

Taking the initiative

Elisa talks about how she takes an active role in her hypothyroidism treatment with Synthroid.

What’s your role in treatment?

Keeping your thyroid hormone levels in balance takes commitment–that's more than just taking a pill. It means:

  • Continuing to take Synthroid the right way
  • Getting your thyroid hormone levels checked regularly
  • Keeping your doctor informed about how you’re feeling and about any new symptoms you are experiencing

Keep reading to see how you can take an active role in managing your hypothyroidism, so you can help keep your thyroid hormone levels where they need to be.

Keeping tabs on TSH

Once you are on a stable dose of Synthroid, it’s important to have your thyroid hormone levels tested every 6 months to a year, or sooner if you’re experiencing symptoms.

A TSH test is used to check the level of thyroid-stimulating hormone (TSH) in the blood, and it helps your doctor determine if you’re receiving the right dose of medicine. And while a TSH test can tell your doctor a lot, it’s just one part of the picture. What your body tells you is also important.

Your dose may need to be adjusted over time

Throughout your lifetime, your doctor may have to adjust your dose of Synthroid. That’s because the amount of thyroid hormone your body needs may change. Some of the reasons for this may include major life events such as pregnancy, menopause, or aging.

Pregnancy

It’s essential to tell your doctor if you’re pregnant or planning on becoming pregnant. The body goes through many changes during pregnancy that may affect your thyroid hormone levels. It’s estimated that 1% to 2% of people develop hypothyroidism during pregnancy despite no prior diagnosis.

Throughout pregnancy, your doctor will need to monitor your thyroid hormone levels, and, if needed, restore your hormone levels with a consistent and precise regimen of Synthroid.

Menopause

Menopause may require you to take estrogen therapy. This is because during menopause your body makes less estrogen. This may require a dose adjustment to your hypothyroidism medicine.

Aging

As you get older, your body may become more susceptible to developing hypothyroidism. Your doctor should test your thyroid hormone regularly during this time.

If you receive a diagnosis for hypothyroidism later in life, your doctor may need to start you on Synthroid. It’s possible they’ll need to slowly start you on medication with smaller doses. Sharing if you have any history of heart disease, stroke, or dementia may help inform your doctor’s dosing decisions.

Commonly asked questions

Myths vs Facts

You need to continue taking Synthroid even after you feel better. What do you think, is this a myth or a fact?

Sorry, that's incorrect. This is a fact.

Hypothyroidism is usually a lifelong condition. While feeling better after starting Synthroid might be a sign that your thyroid levels are restored to normal, you'll need to keep taking Synthroid to maintain these levels. Be sure to always follow your doctor's guidance on taking Synthroid.

See more myths vs facts

Correct! This is a fact.

Hypothyroidism is usually a lifelong condition. While feeling better after starting Synthroid might be a sign that your thyroid levels are restored to normal, you'll need to keep taking Synthroid to maintain these levels. Be sure to always follow your doctor's guidance on taking Synthroid.

See more myths vs facts

Keep communicating with your doctor

Have open and honest conversations with your doctor so they can understand how your treatment is going.

Download conversation starter