USE: SYNTHROID® (levothyroxine sodium) tablets, USP

for oral use is a prescription, man-made thyroid hormone that is used to treat a condition called hypothyroidism. It is meant to replace a hormone that is usually made by your thyroid gland. Generally, thyroid replacement treatment is to be taken for life. SYNTHROID should not be used to treat noncancerous growths or enlargement of the thyroid in patients with normal iodine levels, or in cases of temporary hypothyroidism caused by inflammation of the thyroid gland (thyroiditis).

IMPORTANT SAFETY INFORMATION

  • Thyroid hormones, including SYNTHROID, should not be used either alone or in combination with other drugs for the treatment of obesity or weight loss. In patients with normal thyroid levels, doses of SYNTHROID used daily for hormone replacement are not helpful for weight loss. Larger doses may result in serious or even life-threatening events, especially when used in combination with certain other drugs used to reduce appetite.

  • Do not use SYNTHROID if you have uncorrected adrenal problems.

  • Taking too much levothyroxine has been associated with increased bone loss, especially in women after menopause.

  • Once your doctor has found your specific SYNTHROID dose, it is important to have lab tests done, as ordered by your doctor, at least once a year.

  • Foods like soybean flour, cottonseed meal, walnuts, and dietary fiber may cause your body to absorb less SYNTHROID from the gastrointestinal tract. Grapefruit juice may cause your body to absorb less levothyroxine and may reduce its effect. Let your doctor know if you eat these foods, as your dose of SYNTHROID may need to be adjusted.

  • Use SYNTHROID only as ordered by your doctor. Take SYNTHROID as a single dose, preferably on an empty stomach, one-half to one hour before breakfast.

  • Products such as iron and calcium supplements and antacids can lower your body’s ability to absorb levothyroxine, so SYNTHROID should be taken 4 hours before or after taking these products.

  • Tell your doctor if you are pregnant or breastfeeding or are thinking of becoming pregnant while taking SYNTHROID. Your dose of SYNTHROID may need to be increased during your pregnancy.

  • It may take several weeks before you notice an improvement in your symptoms.

  • Tell your doctor if you are taking any other drugs, including prescription and over-the-counter products.

  • Tell your doctor about any other medical conditions you may have, especially heart disease, diabetes, blood clotting problems, and adrenal or pituitary gland problems. The dose of other drugs you may be taking to control these conditions may have to be changed while you are taking SYNTHROID. If you have diabetes, check your blood sugar levels and/or the glucose in your urine, as ordered by your doctor, and immediately tell your doctor if there are any changes. If you are taking blood thinners, your blood clotting status should be checked often.

  • Tell your doctor or dentist that you are taking SYNTHROID before any surgery.

  • Tell your doctor if you develop any of the following symptoms: rapid or abnormal heartbeat, chest pain, difficulty catching your breath, leg cramps, headache, nervousness, irritability, sleeplessness, shaking, change in appetite, weight gain or loss, vomiting, diarrhea, increased sweating, difficulty tolerating heat, fever, changes in menstrual periods, swollen red bumps on the skin (hives) or skin rash, or any other unusual medical event.

  • Partial hair loss may occur during the first few months you are taking SYNTHROID.

This is the most important safety information you should know about SYNTHROID. For more information, talk with your doctor.

Click here for full Prescribing Information or go to http://www.rxabbvie.com/pdf/synthroid.pdf.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

If you cannot afford your medication, contact www.pparx.org for assistance.

How to take Synthroid

It’s important to take Synthroid exactly as your doctor prescribed. Creating a routine can help you take it the same way every day. Make sure you’re taking Synthroid as your doctor prescribed to help you manage your hypothyroidism.

Tips on taking Synthroid every morning
Take Synthroid once a day at the same time every day

Same time, every morning

Take Synthroid once a day at the same time every day.

Take Synthroid with water only on an empty stomach

TAKE SYNTHROID ALONE

Take Synthroid with water only on an empty stomach. Take Synthroid 4 hours before or after
taking iron or calcium supplements, or antacids. Soy, cottonseed meal, walnuts, fiber, and
grapefuit juice can affect the absorption of Synthroid. If you eat any of these on a regular
basis, talk to your doctor to see if your Synthroid dose should be adjusted.

Do not eat or drink anything other than water for 30 minutes to an hour after taking Synthroid

WAIT 30 minutes to 1 hour before breakfast

This means not eating or drinking anything other than water.

VIDEO GALLERY

DR SEIBEL EXPLAINS THE RIGHT WAY TO TAKE SYNTHROID

Following a consistent routine and avoiding certain medications and supplements when taking Synthroid are important to ensure treatment works the way it should.

DR ROSENTHAL ON
HOW TO TAKE SYNTHROID

Dr Rosenthal discusses the importance of taking Synthroid every morning, tips for making it part of your morning routine, and ensuring you get what your doctor prescribed.

ELISA AND TRACY ON CREATING A MORNING ROUTINE FOR TAKING SYNTHROID

Start your day by consistently taking Synthroid before eating, and know what foods and supplements can interfere with the way your body absorbs Synthroid.

Synthroid Q&A

Are there foods that may interfere with the way Synthroid works?

Click to expand

Yes. Certain foods such as soy, fiber, cottonseed meal, walnuts and grapefruit juice can affect the absorption of Synthroid. If you eat any of these foods on a regular basis, check with your doctor. He or she might have to adjust your dose of Synthroid.

How should I take certain supplements?

Click to expand

Some supplements can affect the way hypothyroidism treatments work. To avoid this, take Synthroid 4 hours before or after taking these supplements:

  • Iron supplements or multivitamins with iron
  • Calcium supplements or multivitamins with calcium
  • Antacids

Remember to take Synthroid every morning on an empty stomach, one-half to one hour before breakfast.

What do I do if I miss a dose?

Click to expand

Call your doctor for advice on what you should do.

What do I do if I miss more than one dose?

Click to expand

Call your doctor for advice on what you should do.

What do I do on weekends and holidays?

Click to expand

Take Synthroid as you usually do, as your doctor prescribed.

What do I do while traveling?

Click to expand

Remember to pack more tablets than you need in your carry-on bag or purse in case you get delayed or decide to stay longer. Plan ahead so you don’t run out of Synthroid while you’re away.

When traveling to another country or time zone, ask the doctor or pharmacist if you need to adjust the time of day for taking Synthroid.

What do I do about refills?

Click to expand

Always refill your Synthroid prescription before it runs out. If your doctor prefers Synthroid, make sure you’re getting Synthroid at every refill. At every refill, check to see if your pill says “SYNTHROID.” Remember, only Synthroid has the name “SYNTHROID” embossed on every pill.

Sign up for the Synthroid Pill & Refill Reminder

Do I still need to take Synthroid if I don’t have any more symptoms?

Click to expand

Even if your hypothyroidism symptoms go away, do not stop taking Synthroid or change the way you take it without talking to your doctor. If you don't take your pills each day as prescribed, your doctor may not be able to tell if your current Synthroid dose is right for you.

How do I store Synthroid?

Click to expand

Keep Synthroid protected in its original bottle or place in a pill case, away from light and moisture, and store at room temperature 25°C (77°F).

Can Synthroid be taken for weight loss?

Click to expand

You should NEVER take hypothyroidism medication, including Synthroid, to treat obesity or for weight loss.

When does my Synthroid dose need to be adjusted, if ever?

Click to expand

When you start taking Synthroid, it’s very important for the doctor to monitor you closely. Your Synthroid dose may need to be adjusted over the course of several weeks before the doctor finds the dose that’s right for you. Throughout your lifetime, the doctor may also need to adjust your dosage. This is because the amount of thyroid hormone you need may change over time or with major life changes such as pregnancy and menopause.

USE

SYNTHROID® (levothyroxine sodium) tablets, for oral use is a prescription, man-made thyroid hormone that is used to treat a condition called hypothyroidism. It is meant to replace a hormone that is usually made by your thyroid gland. Generally, thyroid replacement treatment is to be taken for life. SYNTHROID should not be used to treat noncancerous growths or enlargement of the thyroid in patients with normal iodine levels, or in cases of temporary hypothyroidism caused by inflammation of the thyroid gland (thyroiditis).

IMPORTANT SAFETY INFORMATION

  • Thyroid hormones, including SYNTHROID, should not be used either alone or in combination with other drugs for the treatment of obesity or weight loss. In patients with normal thyroid levels, doses of SYNTHROID used daily for hormone replacement are not helpful for weight loss. Larger doses may result in serious or even life-threatening events, especially when used in combination with certain other drugs used to reduce appetite.

  • Do not use SYNTHROID if you have uncorrected adrenal problems.

  • Taking too much levothyroxine has been associated with increased bone loss, especially in women after menopause.

  • Once your doctor has found your specific SYNTHROID dose, it is important to have lab tests done, as ordered by your doctor, at least once a year.

  • Foods like soybean flour, cottonseed meal, walnuts, and dietary fiber may cause your body to absorb less SYNTHROID from the gastrointestinal tract. Grapefruit juice may cause your body to absorb less levothyroxine and may reduce its effect. Let your doctor know if you eat these foods, as your dose of SYNTHROID may need to be adjusted.

  • Use SYNTHROID only as ordered by your doctor. Take SYNTHROID as a single dose, preferably on an empty stomach, one-half to one hour before breakfast.

  • Products such as iron and calcium supplements and antacids can lower your body’s ability to absorb levothyroxine, so SYNTHROID should be taken 4 hours before or after taking these products.

  • Tell your doctor if you are pregnant or breastfeeding or are thinking of becoming pregnant while taking SYNTHROID. Your dose of SYNTHROID may need to be increased during your pregnancy.

  • It may take several weeks before you notice an improvement in your symptoms.

  • Tell your doctor if you are taking any other drugs, including prescription and over-the-counter products.

  • Tell your doctor about any other medical conditions you may have, especially heart disease, diabetes, blood clotting problems, and adrenal or pituitary gland problems. The dose of other drugs you may be taking to control these conditions may have to be changed while you are taking SYNTHROID. If you have diabetes, check your blood sugar levels and/or the glucose in your urine, as ordered by your doctor, and immediately tell your doctor if there are any changes. If you are taking blood thinners, your blood clotting status should be checked often.

  • Tell your doctor or dentist that you are taking SYNTHROID before any surgery.

  • Tell your doctor if you develop any of the following symptoms: rapid or abnormal heartbeat, chest pain, difficulty catching your breath, leg cramps, headache, nervousness, irritability, sleeplessness, shaking, change in appetite, weight gain or loss, vomiting, diarrhea, increased sweating, difficulty tolerating heat, fever, changes in menstrual periods, swollen red bumps on the skin (hives) or skin rash, or any other unusual medical event.

  • Partial hair loss may occur during the first few months you are taking SYNTHROID.

This is the most important safety information you should know about SYNTHROID. For more information, talk with your doctor.

Click here for full Prescribing Information or go to http://www.rxabbvie.com/pdf/synthroid.pdf.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

If you cannot afford your medication, contact www.pparx.org for assistance.

SYNTHROID TABLETS ARE A PRESCRIPTION MEDICATION.